Module: D_GO:0001666
    Name = response to hypoxia
    Definition = Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.

Response module--------
    Number of tumors that hit the module: 38
    Number of genes in the module: 20
    Genes in the module: ADIPOQ; ADM; ANGPT1; ANGPTL4; BMP2; CAV1; CRYAB; CX3CL1; DPP4; EDN1; EPAS1; FAS; FIGF; LEP; NR4A2; PDGFA; PLAT; SMAD9; SOD3; TGFBR3;
    Modu-hit surivval risk:-------




Perturbation module-------
    Number of genes in the module: 31
    Genes in the module: TCEB1(7c); CCND1(6c); PSMC5(4c); APLP2(1s, 2c); BCOR(3s); CHD3(2s); GTF2I(1s, 1c); DAPK1(2s); TRIP12(1s, 1c); SRRM2(2s); BCL6B(1s, 1c); RNF2(2c); VBP1(1s); MSH4(1s); HIF1A(1c); NFYB(1s); PAN2(1s); CCNDBP1(1c); HNRNPR(1s); MLH3(1c); LUC7L2(1s); HNRNPA1(1s); UBE2E3(1s); EP300(1s); SNRPF(1c); MEPCE(1c); YWHAG(1c); HDAC1; HDAC3; SFN; BCL6;

    Color Codes: