Module: D_GO:0010627
    Name = regulation of intracellular protein kinase cascade
    Definition = Any process that modulates the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

Response module--------
    Number of tumors that hit the module: 308
    Number of genes in the module: 22
    Genes in the module: ADIPOQ; ADRB2; AKR1C3; CAV1; CD36; EGFR; EPHB1; F10; F3; FZD7; IGF1; IL22RA2; IL6; KIT; KLF4; LEP; MID1; NLGN1; NTRK2; PELI2; S100B; SPRY2;
    Modu-hit surivval risk:-------

Perturbation module-------
    Number of genes in the module: 28
    Genes in the module: OTUD7B(3s, 24c); KPNA2(26c); PRKAR1A(1s, 23c); ATF6(2s, 22c); TCEB1(23c); NCOR1(15s, 1c); PBXIP1(1s, 10c); TBL1XR1(8s, 3c); PPP1CA(10c); ARFGEF2(3s, 6c); CDK4(1s, 8c); NCOA2(1s, 7c); SMARCA4(6s, 1c); TRIM28(2s, 5c); VHL(6c); SIRT1(1s, 5c); PLEKHF2(1s, 4c); MCRS1(3s, 1c); USP33(3s, 1c); SNW1(2s, 2c); MAX(3s, 1c); PMS2(1s, 2c); GTF2F1(3c); EP300(2s); YY1(1c); CCDC53(1s); CREB1(1c); HIF1AN;

    Color Codes: