Module: D_GO:0010627
Name = regulation of intracellular protein kinase cascade
Definition = Any process that modulates the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.
Response module--------
Number of tumors that hit the module: 308
Number of genes in the module: 22
Genes in the module: ADIPOQ;
ADRB2;
AKR1C3;
CAV1;
CD36;
EGFR;
EPHB1;
F10;
F3;
FZD7;
IGF1;
IL22RA2;
IL6;
KIT;
KLF4;
LEP;
MID1;
NLGN1;
NTRK2;
PELI2;
S100B;
SPRY2;
Modu-hit surivval risk:-------
Perturbation module-------
Number of genes in the module: 28
Genes in the module: OTUD7B(3s, 24c);
KPNA2(26c);
PRKAR1A(1s, 23c);
ATF6(2s, 22c);
TCEB1(23c);
NCOR1(15s, 1c);
PBXIP1(1s, 10c);
TBL1XR1(8s, 3c);
PPP1CA(10c);
ARFGEF2(3s, 6c);
CDK4(1s, 8c);
NCOA2(1s, 7c);
SMARCA4(6s, 1c);
TRIM28(2s, 5c);
VHL(6c);
SIRT1(1s, 5c);
PLEKHF2(1s, 4c);
MCRS1(3s, 1c);
USP33(3s, 1c);
SNW1(2s, 2c);
MAX(3s, 1c);
PMS2(1s, 2c);
GTF2F1(3c);
EP300(2s);
YY1(1c);
CCDC53(1s);
CREB1(1c);
HIF1AN;
Color Codes: 
