Module: U_GO:0000075
    Name = cell cycle checkpoint
    Definition = A cell cycle regulatory process that controls cell cycle progression by monitoring the timing and integrity of specific cell cycle events. A cell cycle checkpoint encompasses detection of an event or biological quality, signal transduction, and effector processes that delay or stop cell cycle progression in response to a defect.

Response module--------
    Number of tumors that hit the module: 284
    Number of genes in the module: 23
    Genes in the module: BIRC5; BLM; BRIP1; BUB1; BUB1B; CCNA2; CCNB1; CCNB2; CCNE2; CDC20; CDC25C; CDC6; CENPE; CENPF; CHEK1; CLSPN; DTL; MAD2L1; MCM10; MCM4; TTK; UBE2C; ZWINT;
    Modu-hit surivval risk:-------

Perturbation module-------
    Number of genes in the module: 23
    Genes in the module: TP53(149s); YWHAZ(49c); ATAD2(1s, 37c); MED1(37c); MTBP(3s, 33c); MED21(14c); TH1L(3s, 11c); RB1(9s, 4c); ETV6(2s, 11c); HGS(3s, 8c); YWHAB(1s, 9c); KIAA0232(5s, 4c); MDM2(1s, 8c); PAK1(2s, 5c); AR(4s, 2c); EDC3(1s, 3c); HDAC3(2s, 1c); GTF2B(3c); HDAC9(3s); MYC(1s, 2c); POU2F2(3s); ARAF(2c); L3MBTL(2s);

    Color Codes: