Module: U_GO:0000278
    Name = mitotic cell cycle
    Definition = Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.

Response module--------
    Number of tumors that hit the module: 310
    Number of genes in the module: 41
    Genes in the module: AURKA; BIRC5; BUB1; BUB1B; CASC5; CCNA2; CCNB1; CCNB2; CCNE2; CDC20; CDC25C; CDC6; CDCA8; CENPA; CENPE; CENPF; CENPI; CENPM; CENPO; ERCC6L; GINS2; KIF18A; KIF20A; KIF23; KIF2C; MAD2L1; MCM10; MCM4; MLF1IP; MYBL2; NDC80; NEK2; NUF2; PTTG1; RRM2; SGOL1; SPC25; TOP2A; TYMS; UBE2C; ZWINT;
    Modu-hit surivval risk:-------




Perturbation module-------
    Number of genes in the module: 28
    Genes in the module: TP53(155s); GRB7(2s, 48c); YWHAZ(49c); PTK2(2s, 39c); MTBP(3s, 33c); MED30(23c); TAF4(23c); THRA(1s, 17c); MED21(14c); GAB2(2s, 12c); RB1(9s, 4c); ETV6(2s, 11c); MDM2(2s, 9c); E2F3(1s, 8c); TFDP1(1s, 8c); PARP1(1s, 7c); LYN(4s, 2c); MYBL2(1s, 4c); AR(4s, 2c); TSC1(3s, 1c); HIVEP2(2s, 2c); HDAC3(2s, 1c); BRF1(2s, 1c); GRB2(1s, 2c); L3MBTL(2s); PTPN11(2s); UBTF(1c); CBX5;

    Color Codes: