Module: U_GO:0006260
    Name = DNA replication
    Definition = The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.

Response module--------
    Number of tumors that hit the module: 190
    Number of genes in the module: 22
    Genes in the module: BLM; CDC25C; CDC6; CDC7; CDT1; CENPF; CHEK1; CLSPN; DTL; FEN1; GINS1; GINS2; MCM10; MCM2; MCM4; POLG; POLQ; RECQL4; RRM2; TK1; TOP2A; TYMS;
    Modu-hit surivval risk:-------

Perturbation module-------
    Number of genes in the module: 36
    Genes in the module: ATAD2(1s, 33c); KPNA2(1s, 22c); ENY2(17c); AURKA(1s, 13c); RB1(9s, 4c); ETV6(1s, 11c); PHB2(11c); RECQL(1s, 9c); E2F3(1s, 8c); TFDP1(1s, 8c); BRCA1(6s, 2c); PARP1(1s, 7c); KIF2C(2s, 3c); MYBL2(1s, 3c); TPX2(4c); TAF5L(2s, 3c); SKP2(3c); MYC(1s, 2c); GTF2H1(1s, 2c); APOBEC1(1s, 2c); CDK9(3c); POU2F2(3s); HDAC3(1s, 1c); HDAC2(1s, 1c); GTF2I(1s, 1c); L3MBTL(2s); RBL1(1s, 1c); MNAT1(1s, 1c); TAF7(1s, 1c); RBBP7(2c); UBTF(1c); GTF2H4(1c); VDR; ATXN7L3; TAF6; ESR1;

    Color Codes: